Company	Price	Valuation					Profitability					Cash & leverage					Quality				Rating
		P/E	P/B	P/S	EV / EBITDA	DCF upside	Gross margin	Operating margin	Net margin	ROE	ROIC	FCF yield	Debt / equity	Net debt / EBITDA	Interest coverage	Current ratio	Dividend yield	Piotroski (0-9)	Altman Z	Rating score (1-5)
DNLIthis companyDenali Therapeutics Inc.	$20.23	-5.56×	2.86×	0×	-5.48×	-94.9%	0.0%	0.0%	0.0%	-50.6%	-52.6%	-14.6%	0.04×	0.34×	0×	9.16×	0.0%	3	2.05	2	C
ALECAlector, Inc.	$2.45	-1.12×	5.24×	7.63×	-0.99×	-108.0%	54.1%	-692.8%	-679.2%	-466.3%	-62.5%	-114.6%	1.18×	0.22×	0×	3.83×	0.0%	2	-7.33	2	C
AMLXAmylyx Pharmaceuticals, Inc.	$29.48	-7.9×	3.74×	0×	-6.39×	-91.8%	0.0%	0.0%	0.0%	-47.4%	-49.3%	-10.8%	0.02×	1.53×	0×	14.27×	0.0%	3	77.91	2	C
BHVNBiohaven Ltd.	$15.38	-1.65×	23.33×	0×	-1.75×	-103.9%	0.0%	0.0%	0.0%	-1418.8%	-218.4%	-50.2%	5.47×	-0.08×	0×	3.18×	0.0%	3	-15.51	2	C
CGTXCognition Therapeutics, Inc.	$0.73	-4.22×	2.87×	0×	-2.67×	-14.9%	0.0%	0.0%	0.0%	-68.5%	-136.9%	-25.0%	0.02×	1.56×	-3,676.85×	3.45×	0.0%	1	-0.97	2	C+
IONSIonis Pharmaceuticals, Inc.	$28.19	-33.24×	25.88×	13.41×	-52.41×	-292.2%	98.3%	-40.5%	-40.4%	-77.9%	-12.0%	-2.5%	5.35×	-7.89×	-4.22×	3.83×	0.0%	2	0.89	1	D+
Peer median	—	-4.22×	5.24×	0×	-2.67×	-103.9%	0.0%	0.0%	0.0%	-77.9%	-62.5%	-25.0%	1.18×	0.22×	0×	3.83×	0.0%	2	-0.97	2	—