Company	Price	Valuation					Profitability					Cash & leverage					Quality				Rating
		P/E	P/B	P/S	EV / EBITDA	DCF upside	Gross margin	Operating margin	Net margin	ROE	ROIC	FCF yield	Debt / equity	Net debt / EBITDA	Interest coverage	Current ratio	Dividend yield	Piotroski (0-9)	Altman Z	Rating score (1-5)
STOKthis companyStoke Therapeutics, Inc.	$26.86	-264.5×	5.33×	10.19×	-351.59×	-260.5%	100.0%	-11.2%	-3.7%	-2.0%	-5.7%	2.4%	0.01×	15.88×	-2,287.78×	5.28×	0.0%	3	15.59	1	D+
BEAMBeam Therapeutics Inc.	$27.00	-34.22×	2.21×	19.62×	-196.25×	-229.8%	84.0%	-274.6%	-57.2%	-6.5%	-27.4%	-13.1%	0.24×	0.08×	-8.77×	13.09×	0.0%	2	4.01	1	C-
DSGNDesign Therapeutics, Inc.	$10.55	-7.69×	2.53×	0×	-7.55×	-97.5%	0.0%	0.0%	0.0%	-32.8%	-37.1%	-10.1%	0.01×	0.22×	0×	17.14×	0.0%	1	26.54	2	C
IONSIonis Pharmaceuticals, Inc.	$28.19	-33.24×	25.88×	13.41×	-52.41×	-292.2%	98.3%	-40.5%	-40.4%	-77.9%	-12.0%	-2.5%	5.35×	-7.89×	-4.22×	3.83×	0.0%	2	0.89	1	D+
PASGPassage Bio, Inc.	$3.80	-0.82×	2×	0×	-0.34×	101.7%	0.0%	0.0%	0.0%	-242.7%	-100.9%	-84.2%	1.28×	0.5×	0×	2.07×	0.0%	1	-43.91	2	C
WVEWave Life Sciences Ltd.	$3.34	-14.05×	5.45×	67.1×	-11.67×	-66.1%	79.3%	-504.1%	-478.3%	-38.8%	-39.0%	-6.5%	0.03×	2.99×	0×	6.47×	0.0%	2	-0.46	2	C
Peer median	—	-14.05×	2.53×	13.41×	-11.67×	-97.5%	79.3%	-40.5%	-40.4%	-38.8%	-37.1%	-10.1%	0.24×	0.22×	0×	6.47×	0.0%	2	0.89	2	—